How does a nerve transmit impulses?

At rest a nerve cell or fiber has more sodium (NA+) ions in the extracellular fluid and more potassium (K+) ions in the intracellular fluid. There are both NA+ and K+ ion channels in the membrane of the nerve cell and both are closed. Some of the K+ channels are a bit leaky and they let a small flow of k+ ions out of the nerve. This small flow causes the inside of the nerve to be more negative than the outside. We describe the cell as having a potential difference of -70mv. When stimulated to transmit an impulse NA+ channels in the membrane open, allowing NA+ to move into the cell down its diffusion gradient, this makes the inside of the cell less negative (more positive). This happens slowly until the cell reaches a threshold potential difference of -50mv. That is the cell has become sufficiently less negative. Once this threshold has been reached loads of NA+ channels open, allowing the ions to rush into the cell quickly causing the cell to become so much less negative it is positive, a potential difference of +40mv is reached. This positivity within the cell is known as depolarization and stimulates adjacent area of the nerve to also become positive, using the same mechanism. A wave of positivity (or depolarization) then spreads along the nerve, transmitting an impulse.

KW
Answered by Kay W. Biology tutor

3129 Views

See similar Biology A Level tutors

Related Biology A Level answers

All answers ▸

Explain what causes the conduction of impulses along a non-myelinated axon to be slower than along a myelinated axon.


State three differences between daughter cells produced by the process of mitosis and those produced by meiosis.


Explain what is meant by epigenetics and how it can inhibit transcription.


Describe and explain how cell fractionation and ultracentrifugation can be used to isolate mitochondria from a suspension of animal cells.


We're here to help

contact us iconContact ustelephone icon+44 (0) 203 773 6020
Facebook logoInstagram logoLinkedIn logo

MyTutor is part of the IXL family of brands:

© 2026 by IXL Learning