The two are very similar! A synapse is a junction between a Neurone and the next cell. A neuromuscular junction is a kind of synapse, one that occurs between Motor Neurones and Muscle cells. Action potentials are passed from neurones to muscle cells, stimulating movement of the muscle cells. Neuromuscular Junctions work in the same way as a synapse, with a few important differences: - Neuromuscular junctions have more receptors on the postsynaptic membrane than other synapses. - When a motor neurone fires an Action Potential, it always triggers a response in the muscle cell. (This isn't always the case in a synapse between two neurones).