What is the effect of an increase in substrate concentration on the rate of reaction?
An increase in the substrate concentration increases the rate of reaction initially as more enzyme-substrate collisions occur, resultng in more enzyme-substrate complexes being formed.
Eventually maximum velocity is reached meaning that all active site are occupied with substrates so that further increases in the substrate concentration will not cause a change in the reaction rate.
(Enzymes are working at their fastest rate)
PK
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