Explain the process of semi-conservative DNA replication.

  • The enzyme DNA helicase breaks the hydrogen bonds between the two polynucloetide DNA strands causing the double helix to unzip, forming two single strands.

  • Each original single strand then acts as a template for a new strand. Free-floating DNA nucloetides join to the exposed bases on each original template strand via complementary base pairing.

  • The nucloetides of the new strands are joined together by the enzyme DNA polymerase. This forms the sugar-phosphate backbone. Hydrogen bonds form between the bases on the original and new strand and the strands twist to reform the double helix.

  • Each new DNA molecule contains one strand from the original DNA molecule and one new strand, hence the term semi-conservative replication.

Answered by Bardwell J. Biology tutor

50129 Views

See similar Biology A Level tutors

Related Biology A Level answers

All answers ▸

What is transcription and how does it differ in eukaryotes and prokaryotes


If DNA inside a cell is damaged, a protein called p53 halts the cell cycle. With this in mind, explain how a p53 gene mutation could cause cancer to develop.


Explain two properties of water that are vital for aquatic life and explain how these arise


Person A and person B both eat the same high glucose meal. Person A's insulin rises dramatically while Person B's does not. Explain a possible reason why and describe what happens to the glucose once it enters their blood streams.


We're here to help

contact us iconContact usWhatsapp logoMessage us on Whatsapptelephone icon+44 (0) 203 773 6020
Facebook logoInstagram logoLinkedIn logo
Cookie Preferences