How is DNA packaged within Eukaryotic Cell nucleosomes

DNA is wrapped around proteins called histones, to form nucleosomes. Each nucleosome is a histone octomer composed of (H2A, H2B, H3, and H4) subunits with a 1.65 helical turn of 147 nucleotide bases. Nucleosomes then fold upon themselves to form chromatin. 

Loosely packed Chromatin called euchromatin is assoicated with high gene expression whereas densely packed chromatin called heterochromatin is associated with transcriptional repression (gene silencing). 

During metaphase stage of mitosis and meiosis chromatin becomes supercoilded resulting in the ability to see chromosomes under a microscrope. This is essential for the seperation of DNA between daughter cells. 

Answered by Rosewan A. Biology tutor

3499 Views

See similar Biology A Level tutors

Related Biology A Level answers

All answers ▸

What is the function of ATP and explain how is it suitable for its function


Explain the concept of 'chemiosmosis' in oxidative phosphorylation


Explain the route and role of calcium ions in the Sliding Filament theory of muscle contraction


What evidence proves that the Y chromosome determines maleness?


We're here to help

contact us iconContact usWhatsapp logoMessage us on Whatsapptelephone icon+44 (0) 203 773 6020
Facebook logoInstagram logoLinkedIn logo
Cookie Preferences