How does glycolysis produce ATP?

Glycolysis produces energy through the form of ATP. ATP is created directly from glycolysis through the process of substrate-level phosphorylation (SLP) and indirectly by oxidative phosporylation (OP). The three stages of glycolysis are phosphorylation of glucose to glucose-6-phosphate (G6P) which requires ATP, production of triose phosphate (TP) and oxidation of TP to pyruvate, which yields 2 reduced NAD molecules (NADH) and 4 ATP per glucose. 2 ATP molecules were used in the first stage so net ATP gain is 2 ATP. This is substrate-level phosphorylation.  Indirectly, ATP is produced through oxidative phosphorylation. This requires the electron transport chain (ETC) and ATP synthase found on the inner mitochondrial membrane. Briefly, in the ETC the protons from reduced NAD are pumped across the membrane, using the transfer of electrons as an energy source, (from the inner mitochondrial matrix to the intermembrane space) to produce a chemiosmotic gradient. This chemiosmotic gradient provides the energy to drive formation of ATP from ADP and inorganic phosphate within the ATP synthase enzyme.

Answered by Charlie H. Biology tutor

28030 Views

See similar Biology A Level tutors

Related Biology A Level answers

All answers ▸

What is the role of the synapse in neuronal transmission, and why is it important?


Describe how filtration of the blood occurs at the Kidney


What is an enzyme and what effect does temperature have on enzyme activity? (6 marks)


What is chemiosmosis?


We're here to help

contact us iconContact usWhatsapp logoMessage us on Whatsapptelephone icon+44 (0) 203 773 6020
Facebook logoInstagram logoLinkedIn logo

© MyTutorWeb Ltd 2013–2025

Terms & Conditions|Privacy Policy
Cookie Preferences