How does the potential travel between synapses?

The potential or information travels between a pre-synaptic and a post-synaptic neuron. As a reminder, for information, we intend the flow of Na+ and K+ ions between two locations. When the potential arrives at the pre-synaptic neuron terminal, it depolarises the membrane allowing calcium ions (Ca2+) to enter the synapsis. These ions will open the voltage-gated Ca channels between the synapses and promote the synaptic vesicles to fuse to the membrane. The neurotransmitters (contained in the synaptic vesicles) are then released as illustrated.

Now, two events can happen depending on the nature of the neurotransmitter: a new potential can or can not be triggered. If the neurotransmitter is excitatory we will have an EPSP or Excitatory Post Synaptic Potential. The membrane will depolarise promoting the potentials to "pass" from the pre-synaptic to the post-synaptic neuron (physically by lowering the threshold for a new potential to start). On the contrary, if we have an inhibitory neurotransmitter we will have an IPSP or Inhibitory Post Synaptic Potential. Here, the membrane polarises "blocking" the new potential (physically by increasing the threshold for a new potential to start).

Answered by Filippo A. Biology tutor

1907 Views

See similar Biology GCSE tutors

Related Biology GCSE answers

All answers ▸

What is transcription?


Describe how water moves from roots to leaves.


Define osmosis


Bacteria can become resistant to antibiotics, how can doctors reduce the number of resistant bacteria? (2 marks)


We're here to help

contact us iconContact usWhatsapp logoMessage us on Whatsapptelephone icon+44 (0) 203 773 6020
Facebook logoInstagram logoLinkedIn logo
Cookie Preferences