First DNA helicase unwinds the strand of DNA. Then, DNA polymerase binds to the anti-sense strand of the DNA and adds RNA nucleotides in a sequence complementary to the strand of DNA. The DNA polymerase catalyses the formation of phosphodiester bonds between the RNA nucleotides, forming a strand of mRNA. The mRNA leaves the nucleous via a pore in the nuclear membrane and attaches to a ribosome. tRNAs enter the ribosome and complemenatary tRNAs bind to the correct codons on the mRNA. The tRNAs carry amino acids. The ribosome catalyses the formation of peptide bonds between the amino acids. This forms the primary structure of the protein.