Explain how a change in a sequence of DNA bases could result in a non-functional enzyme

A mutation in the DNA sequence may lead to a different amino acid sequence may lead to a different amino acid being produced in the primary protein structure of the enzyme during translation. This may cause errors in protein folding - causing the protein to form different three-dimensional tertiary structure. If this occurs in the active site of the enzyme, successful enzyme-substrate complexes may no longer be able to form

YA
Answered by Yusuf A. Biology tutor

20566 Views

See similar Biology A Level tutors

Related Biology A Level answers

All answers ▸

Why may a rise in testosterone above normal cause a subsequent decrease in the hormone?


After one molecule of oxygen has bound to Haemoglobin, it is easier for a second molecule of oxygen to bind. Explain Why?


How do mutations make non-functional enzymes?


how is an ation potential generated?


We're here to help

contact us iconContact ustelephone icon+44 (0) 203 773 6020
Facebook logoInstagram logoLinkedIn logo

© MyTutorWeb Ltd 2013–2025

Terms & Conditions|Privacy Policy
Cookie Preferences