Describe the events that take place in a neurone which produce an action potential

  • The action potential begins when the stimulus exceeds the threshold.
    - The voltage gated sodium ion channels open.
    - Sodium ions diffuse into the axon down an electrochemical gradient.
    - Positive feedback occurs (more sodium ion channels open).
    - This depolarises the membrane.
    - The membrane potential reverses from -65mV to +40mV.
    - The voltage gated potassium ion channels now open.
    - Potassium ions diffuse out of the axon down an electrochemical gradient.
    - The sodium ion channels close.
    - Hyperpolarisation occurs.
    - But the sodium potassium pump then restores the resting potential by actively transporting 3 Na+ out of the axon and 2K+ into the axon.
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