Describe the process of an action potential through a neuron

A stimulus (e.g. change in temperature, pain, etc.) results in the depolarisation of the membrane of the neuronal cell body. This depolarisation causes the membrane potential to rise from resting potential (-70mV) to a threshold poential (-55mV). At the threshold potential, voltage-gated sodium ion channels will open. This results in a influx of sodium ions into the cell which causes the membrane to depolarise and open neighbouring voltage-gated sodium ion channels further along the membrane, consquently initiating an action potential along the neuron (like a domino effect). Once a threshold has been reached (about +40mV), sodium ion channels will close and potassium ion channels will open, allowing an efflux of potassium ions and causing the neuron to repolarise back to a negative membrane potential. There is a brief period of hyperpolarisation due to the action of leaky potassium channels. Sodium pumps (Na+/K+ pumps) will actively transport 3 sodium ions out and 2 potassium ions in to bring the membrane potential back to resting potential.

Answered by Emily C. Biology tutor

3781 Views

See similar Biology A Level tutors

Related Biology A Level answers

All answers ▸

Why does oxygen bind to haemoglobin easier the second time?


Outline the importance of the junctions between neurones in the functioning of the nervous system


Some phenotypes, such as colour-blindness, are caused by sex-linked genes. Explain why colour-blindness is more common in men than in women


Explain the process of synaptic transmission (6 marks).


We're here to help

contact us iconContact usWhatsapp logoMessage us on Whatsapptelephone icon+44 (0) 203 773 6020
Facebook logoInstagram logoLinkedIn logo

© MyTutorWeb Ltd 2013–2024

Terms & Conditions|Privacy Policy
Cookie Preferences