Describe the process of oxidative phosphorylation

There are four main electron carrier protein complexes in the inner mitochondrial complex, which use the energy from the transfer of electrons to pump H+ into the intermembrane space, this is known as the electron transport chain. H+ and e- are generated from the breakdown (re-oxidisation) of NADH and FADH2 (at Complexes I and II respectively) and are produced by the Krebs cycle. The H+ build up in the intermembrane space creates a proton gradient which causes the H+ ions to diffuse through a protein channel associated with ATP synthase which uses the gradient's energy to facilitate the formation of ATP from ADP + Pi. The electrons left over from the transport chain react with oxygen, as the terminal reaction of the electron transport chain and create oxygen radicals. These oxygen radicals react with the H+ ions in the mitochondrial matrix to produce water.

TB

Related Biology A Level answers

All answers ▸

What is the difference between haemodialysis and peritoneal dialysis?


What is the role of the Loop of Henle in urine production?


Give two ways in which the structure of starch and cellulose are similar and different to one another.


Explain the role of anti-diuretic hormone in osmotic homeostasis.