When people have liver failure they may get swollen legs due to oedema. Explain the processes behind this.

The liver is responsible for making proteins found in the blood which help to maintain it's "oncotic pressure", the 'pull' factor that holds water inside the blood vessels. These proteins cannot pass through the blood vessels into the tissues, so they hold water within the blood. When the liver fails, these proteins are not produced and thus the 'oncotic pressure' of the blood falls; without this, water leaks out of the blood vessels through osmosis, as the tissues now have a higher oncotic pressure. Leakage of water into the tissues causes them to swell up, producing the oedema.

JI
Answered by Joy I. Human Biology tutor

3128 Views

See similar Human Biology A Level tutors

Related Human Biology A Level answers

All answers ▸

Why is there no wave for atrial repolarisation in the electrocardiogram?


If a person has a very poor diet they may have a very low concentration of proteins in the blood. This may cause oedema. Explain Why


What is the mechanism which leads to an increase in heart rate during exercise?


‘Smokers suffer from more lower respiratory tract infections.’ Justify this statement in light of respiratory tract protection mechanisms.


We're here to help

contact us iconContact ustelephone icon+44 (0) 203 773 6020
Facebook logoInstagram logoLinkedIn logo

MyTutor is part of the IXL family of brands:

© 2026 by IXL Learning