Explain the route and role of calcium ions in the Sliding Filament theory of muscle contraction

ROUTE: when an action potential arrives at the neuromuscular junction, Calcium ions are released from the sarcoplasmic reticulum, into the sarcoplasm, where they bind to the troponin molecules on the tropomyosin. After contraction of the muscle fibre, the calcium ions are taken up by the sarcoplasmic reticulum for relaxation of the muscle. ROLE: When the calcium ions bind to troponin, they cause the tropmyosin molecules to move out of the way to expose the myosin binding sites on the actin filament. The abundance of calcium ions in the sarcoplasm regulates the contraction and relaxation of the muscle fibre.

Answered by Erin C. Biology tutor

14264 Views

See similar Biology A Level tutors

Related Biology A Level answers

All answers ▸

In a population of 1000 lemmings there are two alleles for skin colour, the dominant colour being cream (C) and the recessive being white (c). 350 individuals have white skin. Use Hardy-Weinberg to predict the number of homozygous recessive individuals.


How do you test for monosaccharides/disaccharides?


How would you explain oxidative phosphorylation and chemiosmosis?


Describe the sliding filament theory.


We're here to help

contact us iconContact usWhatsapp logoMessage us on Whatsapptelephone icon+44 (0) 203 773 6020
Facebook logoInstagram logoLinkedIn logo
Cookie Preferences