When stimulated, how does the Pacinian corpuscle produce a generator potential?
The Pacinican corpuscle is a mechanical pressure receptor around the end of a sensory neurone. When pressure is detected, the receptor is compressed, opening ligand-gated sodium ion channels. This allows sodium ions to enter the neurone, depolarising the membrane towards the threshold potential, at approximately -55mV. If the depolarisation reaches -55mV then an action potential will be intitiated and propagated throughout the neurone.
EJ
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