While they are both nucleic acids, there are going to be a lot of differences between DNA and RNA, starting from the names (deoxyibonucleic acid and ribonucleic acid). In terms of structure, DNA is double stranded which means it has two nucleotide strands which are anti-parallel, whereas RNA is single stranded. Base-pairing is another important difference between the nucleic acids. Although they both have 4 bases containing nitrogen, divided into purines and pyrimidines, in DNA Adenine links to Thymine (double bond) and Cytosine links to Guanine (triple bond) and in RNA Thymine is replaced by Uracil, so A-U.