Why is DNA replication called semi-conservative replication?

Semi-conservative replication refers to replication of DNA in which the newly produced DNA molecules will contain 1 strand from the original DNA and a another strand that had been newly synthesised. In order to understand this further, it is best to look at how DNA replication occurs. We start with a simple DNA molecule, consisted of 2 strands of DNA tightly wound together. If we want to replicate the DNA we will have to do 2 things first the DNA molecule will have to uncoil and secondly we must break the hydrogen bonds between the complementary bases of the 2 DNA strands (remember that complementary bases A-T and C-G hydrogen bond). To be able to break apart the DNA molecule we must use a special enzyme called DNA helicase (it will catalyse the breakdown of the hydrogen bonds). Both strands of DNA molecule will now act as template strands for the formation of 2 new DNA molecules. In this instance free DNA nucleotides (recall what nucleotides are) will complementary base pair with the exposed DNA bases on each of the template strands. Now that the bases have been bound we now need to join the nucleotides together to reform the DNA strand, we use an enzyme called DNA polymerase (look at name going from monomers to polymers). Now that the strands are formed, the 2 strands will coil together once more and we receive the newly synthesised DNA strands. If you look at each new DNA molecule made, you can see that they contain one new and one old strand of DNA as shown by the different colours.

AA
Answered by Awais A. Biology tutor

14584 Views

See similar Biology A Level tutors

Related Biology A Level answers

All answers ▸

Describe how fertiliser run-off can cause damage to a lake's ecosystem.


What might happen to the rate of glucose production as the temperature of a solution of sucrose and (human) sucrase was raised from 33°C to 43°C and why?


Mitosis is the process of cell division, it occurs in humans and in plants. Compare and contrast the process of mitosis in human cells and in plant cells (5 marks)


What is mitosis?


We're here to help

contact us iconContact ustelephone icon+44 (0) 203 773 6020
Facebook logoInstagram logoLinkedIn logo

MyTutor is part of the IXL family of brands:

© 2025 by IXL Learning