Where do all the stages of respiration (aerobic and anaerobic) happen?

The first part of aerobic respiration is to convert glucose into pyruvate in a series of reactions known as glycolysis, which happens in the cytoplasm of cells. Glycolysis consumes 2 molecules of ATP and produces 4 by substrate-level phosphorylation, giving a net gain of 2 ATPs, whilst also generating 2 molecules of NADH. The pyruvate molecules from glycolysis can go into one of 2 pathways - anaerobic fermentation or the link reaction if oxygen is present. Anaerobic fermentation also happens in the cytoplasm of the cell and produces 2 molecules of lactic acid while regenerating 2 molecules of NAD+.If oxygen is present, pyruvate molecules will undergo the link reaction in the matrix of the mitochondria in the cell. This combines pyruvate with a molecule of coenzyme A to produce acetyl-CoA (which can enter the Krebs Cycle), NADH and carbon dioxide as a byproduct. The acetyl-CoA enters the Krebs cycle which also takes place in the mitochondria to produce lots more electron carrying molecules - NADH and FADH2 to go to oxidative phosphorylation in the inner mitochondrial membrane. Overall, producing around 38 molecules of ATP.

Answered by Eve L. Biology tutor

1927 Views

See similar Biology A Level tutors

Related Biology A Level answers

All answers ▸

How does speciation occur?


Describe the processes which occur that allow synaptic transmission


What is the definition of a pathogen and give two examples. (3 marks)


Describe the process of PCR, including what is needed.


We're here to help

contact us iconContact usWhatsapp logoMessage us on Whatsapptelephone icon+44 (0) 203 773 6020
Facebook logoInstagram logoLinkedIn logo
Cookie Preferences