How much water is in blood is defined by its osmolarity, i.e. how concentrated solutes such as sodium ions are in the blood. The pituitary gland in the brain releases ADH (Anti Diuretic Hormone) if there is not enough water in the blood, and the osmolarity is high. ADH acts in the distal convoluted tubule of the kidney which caused very concentrated urine to be made, thus conserving water. If there is too much water in the blood, less ADH is released causing dilue urine and the loss of water.