What role do natural killer cells and phagocytes play in the specific and non-specific destruction of pathogens?

With regards to the non-specific immune response, phagocytes engulf and digest pathogens through phagocytosis. Natural killer cells detect infected cells through monitoring the presence of particular signals on its cell surface. If detected, the natural killer cell can then release substances into the infected cell to trigger apoptosis. Phagocytes and natural killer cells are not directly involved in the specific immune response, but they can produce cytokines that attract the immune cells necessary to begin the specific immune response.

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