ADH (anti-diuretic hormone) is a hormone that is released by the brain. It is released if there is too much water loss via the kidneys, if this occurs, then the pituitary gland releases ADH into the bloodstream. When ADH arrives at the kidneys, it causes the kidney nephrons to become more permeable, this allows for water reabsorption and prevents excess water loss. If there is more water than what is needed in the body, then this is detected by the brain and causes the pituitary gland to release less ADH and causes less reabsorption of water in the nephrons, causing a reduction in the amount of water in the body.This process is known as osmoregulation and ADH acts as a negative feedback, making sure that the amount of water in the body is not too high or not too low.