What is the cAMP cascade and where does it occur?

The cAMP cascade describes an intracellular process that occurs upon activation of glucagon and adrenaline receptors. Glucagon receptors are present mainly in the liver, where they activate enzymes that convert glycogen, glycerol, and amino acids to glucose. Thus, the liver is the main place that releases glucose into the blood once a person is in the fasted state. Adrenaline receptors are present throughout the body, and in the heart for example, they respond with the cAMP cascade to result in increased heart rate. A summary of the cascade is as follows:The hormone binds to its receptor -> this activates the enzyme adenylate cyclase -> the enzyme catalyses the following reaction: ATP -> cyclic AMP (cAMP) -> this activates a protein called protein kinase A. This goes on to phosphorylate and thus activate the enzymes in question.

Answered by Fareema F. Biology tutor

6496 Views

See similar Biology A Level tutors

Related Biology A Level answers

All answers ▸

Describe the steps following the arrival of an action potential to the pre-synaptic bulb allowing for transmission of a signal across a synapse.


What is the function of ATP and explain how is it suitable for its function


Can you please explain the lock and key model of enzyme action to me?


What is the difference between mitosis and meiosis?


We're here to help

contact us iconContact usWhatsapp logoMessage us on Whatsapptelephone icon+44 (0) 203 773 6020
Facebook logoInstagram logoLinkedIn logo

© MyTutorWeb Ltd 2013–2024

Terms & Conditions|Privacy Policy
Cookie Preferences