Explain how an action potential is generated in a sensory neurone.

DIAGRAM
At rest, there is a potential difference across the cell surface membrane of -60mV maintained by sodium-potassium ion pumps which pump 3 Na+ ions out of the cell for every 2 K+ ions pumped in. When a stimulus is detected by a receptor some of the sodium ion channels open, allowing Na+ ions to diffuse into the cell down the concentration gradient. This causes a depolarisation of the membrane known as a generator potential. If this generator potential exceeds the threshold potential (-50mV), voltage-gated sodium ion channels will open triggering diffusion of more Na+ ions into the neurone and the membrane will depolarise, generating an action potential of +40mV.
Once the action potential is reached, the sodium ion channels close and potassium ion channels open. K+ ions diffuse out of the cell causing repolarisation of the membrane. However this overshoots leading to hyperpolarisation. At this point the potassium ion channels also close and the sodium-potassium ion pumps return the potential difference to -60mV via active transport.

Answered by Alastair M. Biology tutor

2092 Views

See similar Biology GCSE tutors

Related Biology GCSE answers

All answers ▸

What's the difference between diffusion and osmosis?


Sandeep has been fasting and is not drinking water during the daytime. Name the hormone and explain the sequence of events involving this hormone, that occur during the day to maintain Sandeep's water balance.


Describe how pancreatic hormones regulate blood glucose homeostasis.


Describe the mechanism of inhalation.


We're here to help

contact us iconContact usWhatsapp logoMessage us on Whatsapptelephone icon+44 (0) 203 773 6020
Facebook logoInstagram logoLinkedIn logo

© MyTutorWeb Ltd 2013–2025

Terms & Conditions|Privacy Policy
Cookie Preferences