Firstly, calculate the initial value of of M, by substituting t = 0 into the equation M=300e-0.05tInitially, M0= 300e0=300 x 1 = 300When the substance mass has decreased to half its initial value, M = 0.5 x 300 = 150.Hence, we have the equation 300e-0.05t= 150Solve: e-0.05t= 0.5-0.05t= ln 0.5t = -20ln0.5= 13.8629...= 13.9 (3 s.f.)It will take 13.9 minutes for the substance mass to decrease to half its original value.