Describe the process of DNA replication

DNA replicates via semi-conservative replication. This means one strand acts as the template strand. The enzyme DNA Helicase breaks the hydrogen bonds between base pairs in DNA. This unwinds the DNA, exposing the template strand. DNA free nucleotides are able to bind to the exposed template strand via complimentary base pairing. This process allows hydrogen bonds between bases to form. The sugar-phosphate backbone is formed by the formation of phosphodiester bonds between the phosphate group of one nucleotide and the deoxyribose sugar of the next nucleotide. This is catalysed by the enzyme DNA Polymerase, in the 5' to 3' direction.
Extension: This occurs continuously on the leading strand, but forms fragments called Ozaki fragments on the lagging strand. The fragments are then joined by DNA ligase.

Answered by Joanna D. Biology tutor

2024 Views

See similar Biology A Level tutors

Related Biology A Level answers

All answers ▸

What are different animal's cognitive limitations? How can we observe this in the wild?


how does oxidative phosphorylation work in aerobic respiration


When a new antigen is presented to the immune system, an immune response leads to antibodies are released. The second time this happens it is much faster - explain why


What occurs during an action potential in a neuron?


We're here to help

contact us iconContact usWhatsapp logoMessage us on Whatsapptelephone icon+44 (0) 203 773 6020
Facebook logoInstagram logoLinkedIn logo
Cookie Preferences