crossing over and random orientation of chromosomes occurs in Meiosis I;o Random orientation: ▪ Random orientation of homologous chromosomes creates genetic variation. ▪ There are over 8 million ways that chromosomes can be oriented during meiosis. o Crossing over: ▪ Crossing over allows linked genes to be reshuffled in prophase I. ▪ It increases the number of allele combinations and thus genetic diversity.