What is a genetic mutation?

A mutation is a random change in the amount of DNA or sequence of DNA nucleotides within a cell. DNA is a double helix with two polynucleotide strands joined by hydrogen bonds between complementary base pairs. This structure is usually very stable, but mutations can randomly occur during DNA replication and also in the presence of mutagens (e.g. ionising radiation). Genetic mutations involve insertions, deletions, substitutions, inversions, changes in the number of repeat units, deamination (e.g. cytosine can be deaminated to form uracil) or depurination (resulting in the conversion of a nucleotide into a sugar-phosphate residue). 

Answered by Krupa R. Biology tutor

6090 Views

See similar Biology A Level tutors

Related Biology A Level answers

All answers ▸

What is the role of the kidneys in osmoregulation?


Briefly describe how the autonomic nervous system returns internal body temperature to normal following a rise in body temperature


What is genetic diversity?


Define homeostasis and explain it in the context of blood glucose concentration.


We're here to help

contact us iconContact usWhatsapp logoMessage us on Whatsapptelephone icon+44 (0) 203 773 6020
Facebook logoInstagram logoLinkedIn logo

© MyTutorWeb Ltd 2013–2025

Terms & Conditions|Privacy Policy
Cookie Preferences