How do skeletal muscles contract ?

A motor neuron stimulates the sarcoplasmic reticulum, causing it to release Calcium ions. The calcium ions binds to the toponin that is blocking the myosin binding site on the acting filament, the binding of the calcium causes toponin to change its shape and it becomes tropomyosin, this exposes the myosin binding site on the actin. Once the site is exposed the myosin head binds to the actin forming a cross bridge. ATP binds to the myosin head causing the cross bridge to break. ATP hydrolysis causes the myosin heads to change position and swivel, moving them towards the next actin binding site, this allows the myosin head to bind to other regions on the actin. The myosin drags the actin towards the centre causing the sacromere to shorten. This sliding or the two filaments allows the muscle to contact.

Answered by Akshita N. Biology tutor

1202 Views

See similar Biology IB tutors

Related Biology IB answers

All answers ▸

Explain DNA replication


Can you explain the oxygen dissociation curve? and the Bohr Shift?


Explain the oxygen dissociation curve and the role of Bohr shift.


Explain the sliding-filament theory


We're here to help

contact us iconContact usWhatsapp logoMessage us on Whatsapptelephone icon+44 (0) 203 773 6020
Facebook logoInstagram logoLinkedIn logo
Cookie Preferences