Describe how the ultrastructure of the glomerulus and Bowman’s capsule facilitate ultrafiltration.

The filtration barrier between blood and filtrate comprises of 3 main structures: fenestrated endothelium of the arteriole, glomerular basement membrane and specialised cells called podocytes with slit diaphragms encapsulating the blood vessel. The barrier prevents passage of cells and big molecules such as proteins. The filtrate contains water, electrolytes and sometimes glucose that is later reabsorbed in the nephron.Moreover, ultrafilration occurs thanks to high hydrostatic pressure that pushes the blood against the barrier. What facilitates the formation of the high pressure is the fact that the afferent (entering) arteriole is wider than the efferent (leaving) arteriole, hence it is easier for the blood to enter the glomerulus than leave it.

Answered by Zuzanna B. Biology tutor

3721 Views

See similar Biology A Level tutors

Related Biology A Level answers

All answers ▸

What are the models for enzyme action and how to remember the differences?


How do electrical impulses control the regular beating of the heart?


Describe the process that converts a genetic sequence on messenger RNA into the primary sequence of a protein


Some phenotypes, such as colour-blindness, are caused by sex-linked genes. Explain why colour-blindness is more common in men than in women


We're here to help

contact us iconContact usWhatsapp logoMessage us on Whatsapptelephone icon+44 (0) 203 773 6020
Facebook logoInstagram logoLinkedIn logo

© MyTutorWeb Ltd 2013–2024

Terms & Conditions|Privacy Policy
Cookie Preferences