What are the main differences between an eukaryote and a prokaryote cell

First of all is very important to remember that prokaryote cells are much smaller than eukaryote cells. The main difference between eukaryotes and prokaryotes is that the first ones have a nucleus and membrane bound organelles whereas the latter don’t. Eukaryotes have 80s ribosomes, linear DNA present in a nucleus which is surrounded by a nuclear envelope and a plasma membrane (a cell wall is present in plant cells and fungi); prokaryotes have 70s ribosomes, free circular genetic material (plasmid), and a plasma membrane surrounded by a cell wall and sometimes a capsule, which can be covered in pili.