What is Le Chatelier's principle?

If a reaction at equilibrium is subjected to a change in concentration, pressure or temperature, the position of equilibrium will move to counteract that change.

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PharmaPlus, a drug developer, is required by law to carry out clinical trials on the novel drug ‘AccuPreasure’. AccuPreasure is to be marketed for control of high blood pressure. Give three questions that clinical trials are designed to answer.