How are amino acids involved in condensation and hydrolysis reactions?

A condensation reaction is where two small molecules react together to form a larger molecule with the elimination of a small molecule like water. Two amino acids can react in a condensation reaction to form a peptide bond and release water. This forms a dipeptide. Many condensation reactions can occur between amino acids to build up a peptide or protein chain.

Hydrolysis is the breaking of a bond by reacting with water. It can be catalysed with acid or alkali. Proteins and peptide chains can undergo hydrolysis to break the peptide bond and form its constituent amino acids.

Acid hydrolysis usually involves heating the protein under reflux with acid e.g. 6 moldm-3 HCl(aq). This will use water to break the bond and form amino acids often with a positve charge due to the low pH depending on their isoelectric point.

Alkaline hydrolysis often involves heating just above 100°C with NaOH. This will form amino acid salts so on the carboxyl group will be COO-Na+.

Answered by Zoe C. Chemistry tutor

29548 Views

See similar Chemistry A Level tutors

Related Chemistry A Level answers

All answers ▸

Write a balanced equation for the oxidation of Iron from the 2+ oxidation state to the 3+ oxidation state using the manganate ion.


What does Le Chatelier's principle say happens to an equilibrium when temperature is changed or a catalyst is added?


How can you tell what shape a molecule is going to be?


The reversible reaction 2 SO2 (g) + O2 (g) <-> 2 SO3 (g) has a delta H value of -197 kJ/mol. Use Le Chatelier's principle to explain what conditions would give the highest equilibrium yield and why industry uses different conditions. (5 marks)


We're here to help

contact us iconContact usWhatsapp logoMessage us on Whatsapptelephone icon+44 (0) 203 773 6020
Facebook logoInstagram logoLinkedIn logo
Cookie Preferences