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Tetrodotoxin (TTX) is a chemical found in pufferfish which binds to voltage-gated sodium channels causing inactivation via a conformational change. Poisoning can result in paralysis leading to death. How might this occur? (4 marks)

This question asks about nerve action potential generation. There are a couple of clues - these include 'voltage-gated sodium channels' and 'paralysis' which suggests the idea of failure of impulse transm...

Answered by Rafee A. Biology tutor
3809 Views

I buy a car from a dealership for £3500. The car depreciates in value for every year I own it. What is the value of the car after I have owned it for 18 months if it depreciates at a rate of 5 percent?

This is a compound interest problem. Here we have to put 18 months in terms of years. There are 12 months in a year, so 18 months is a year and 6 months.
6 months is half a year, so 18 months repres...

Answered by Lauren M. Maths tutor
2857 Views

In triangle XYZ: XZ = 10 cm; YZ = 8 cm; cos Z = 1/8. Calculate the length of XY.

We can use the cosine rule to determine the lenght of XY.
XY2 = 102+82-2108cos ZXY2 = 100+64-180(1/8) = 144XY = 12

Answered by Vencel H. Maths tutor
6006 Views

Explain why Hitler was able to create a dictatorship in the period February 1933 to August 1934. You may use the following in your answer: the Reichstag Fire; the Night of the Long Knives. You must also use information of your own. (12)(Edexcel past Q)

It is important to recognise immediately that this question is asking you WHY Hitler was able to create a dictatorship. Detailing or describing important factors with no explicit l...

Answered by William B. History tutor
10009 Views

Evaluate the evidence used to reconstruct climate change

The command word is ‘evaluate’, requiring you to assess the relative importance or validity of the evidence. Therefore, your conclusion should include a judgement, for example, of the most or least import...

Answered by Emma M. Geography tutor
2869 Views

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